About Golgin subfamily A member 6-like protein 10
Golgin subfamily A member 6-like protein 10 (GOLGA6L10) is a protein
from Homo sapiens identified by UniProt accession
A6NI86, 522 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Golgin subfamily A member 6-like protein 10 |
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| UniProt accession | A6NI86 |
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| Gene | GOLGA6L10 |
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| Organism | Homo sapiens |
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| Length | 522 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (15)
Diseases linked to this target (Open Targets).
- excessive daytime sleepiness measurement · score 0.16
- daytime rest measurement · score 0.06
- cerebellar volume measurement · score 0.06
- episodic memory · score 0.05
- self reported educational attainment · score 0.05
- intelligence · score 0.05
- testosterone measurement · score 0.04
- cognitive function measurement · score 0.04
- schizophrenia · score 0.04
- age at first sexual intercourse measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NI86-F1 | alphafold | PREDICTED | 73.30 | — |
Amino-acid sequence (522 residues)
MWPQPRLPPH PAMSEKTQQG KLAAAKKKLK AYWQRKSPGI PAGANRKKKV NGSSPDTATS GGYHSPGDSA TGIYGEGRAS STTLQDLESQ YQELAVALDS SSAIISQLTE NINSLVRTSK EEKKHEIHLV QKLGRSLFKL KNQTAEPLAP EPPAGPSKVE QLQDETNHLR KELESVGRQL QAEVENNQML SLLNRRQEER LREQEERLHE QEERLHEQEE RLCEQEERLR EQEERLCEQE ERLREQEERL CEQEERLREQ EERLCEQEER LREQEERLRE QEERLCEQEE RLCEQEERLR EQEERLCEQE ERLCEQEERL CEQEKLPGQE RLLEEVEKLL EQERRQEEQE RLLERERLLD EVEELLEQER LRQQDERLWQ QETLRELERL RELERLRELE RMLELGWEAL YEQRAEPRSG FEELNNENKS TLQLEQQVKE LEKSGGAEEP RGSESAAAAR PVPGAPVPQG AWMCGQAGWT PQEHPGLSGE AVGTGEAAGG AEEAACHSFR AAENRELNIT II
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