Sperm annulus positioning complex subunit Chibby3…

About Sperm annulus positioning complex subunit Chibby3

Sperm annulus positioning complex subunit Chibby3 (CBY3) is a protein from Homo sapiens identified by UniProt accession A6NI87, 242 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Sperm annulus positioning complex subunit Chibby3
UniProt accession	A6NI87
Gene	CBY3
Organism	Homo sapiens
Length	242 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.27
lymphocyte count · score 0.08
myeloid white cell count · score 0.07
neutrophil count · score 0.06
leukocyte count · score 0.05
male infertility · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NI87-F1	alphafold	PREDICTED	67.57	—

Amino-acid sequence (242 residues)

MWASRDHLPE PDLGDAAPPG SPSSFWTSGL PRQERSTSRQ RSRGSPSSTC VPYKVHALAT FECSATSHAS RLWQTLQQFW ADHISRPFSP RRPPLRRMPS LSTFYLLDHN TRQAELGLAY GAPCMRLSNQ AFVFRGGRWT TESQLARTRS PLLSRTAWGW KAQVQRSKSQ VLLEENNYLK LQQELLIDML TETMARMHLL EKQRNPEVIP TAAARAGQRK MRKRAGASAG VLMIQPCALD SQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Sperm annulus positioning complex subunit Chibby3 (CBY3)