About Solute carrier family 15 member 5
Solute carrier family 15 member 5 (SLC15A5) is a protein
from Homo sapiens identified by UniProt accession
A6NIM6, 579 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Solute carrier family 15 member 5 |
|---|
| UniProt accession | A6NIM6 |
|---|
| Gene | SLC15A5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 579 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- body mass index · score 0.42
- Antidepressant use measurement · score 0.34
- body weight · score 0.33
- self reported educational attainment · score 0.32
- body height · score 0.30
- mood instability measurement · score 0.30
- psychological resilience measurement · score 0.27
- risky sexual behaviour measurement · score 0.27
- Red cell distribution width · score 0.27
- chronotype measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NIM6-F1 | alphafold | PREDICTED | 76.26 | — |
Amino-acid sequence (579 residues)
MSVTGFTITD EKVHLYHSIE KEKTVRHIGD LCSSHSVKKI QVGICLLLVE LCERFTFFEV VCNMIPFCTI KLGYHNCQAA ILNLCFIGTS ILTPVFVRWL TDVYLGRNKL VYICLFLHFL GTALLSVVAF PLEDFYLGTY HAVNNIPKTE QHRLFYVALL TICLGIGGVR AIVCPLGAFG LQEYGSQKTM SFFNWFYWLM NLNATIVFLG ISYIQHSQAW ALVLLIPFMS MLMAVITLHM IYYNLIYQSE KRCSLLTGVG VLVSALKTCH PQYCHLGRDV TSQLDHAKEK NGGCYSELHV EDTTFFLTLL PLFIFQLLYR MCIMQIPSGY YLQTMNSNLN LDGFLLPIAV MNAISSLPLL ILAPFLEYFS TCLFPSKRVG SFLSTCIIAG NLFAALSVMI AGFFEIHRKH FPAVEQPLSG KVLTVSSMPC FYLILQYVLL GVAETLVNPA LSVISYRFVP SNVRGTSMNF LTLFNGFGCF TGALLVKLVY LISDGNWFPN TLNKGNLESF FFFLASLTLL NVLGFCSVSQ RYCNLNHFNA QNIRGSNLEE TLLLHEKSLK FYGSIQEFSS SIDLWETAL
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