Methyl-CpG-binding domain protein 3-like 5 (MBD3L5)

About Methyl-CpG-binding domain protein 3-like 5

Methyl-CpG-binding domain protein 3-like 5 (MBD3L5) is a protein from Homo sapiens identified by UniProt accession A6NJ08, 208 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Methyl-CpG-binding domain protein 3-like 5
UniProt accession	A6NJ08
Gene	MBD3L5
Organism	Homo sapiens
Length	208 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

bone density · score 0.03
urate measurement · score 0.03
refractive error measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NJ08-F1	alphafold	PREDICTED	65.37	—

Amino-acid sequence (208 residues)

MGEPAFTSFP SPPVLGKLKR NMMPWALQKK REIHMAKAHR RRAARSALPM RLTSCIFRRP VTRIRSHPDN QVRRRKGDEH LEKPQQLCAY RRLQALQPCS SQGEGSSPLH LESVLSILAP GTAGESLDRA GAERVRIPLE PTPGRFPAVA GGPTPGMGCQ LPPPLSGQLV TPADIRRQAR RVKKARERLA KALQADRLAR QAEMLTGG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards