About Arginine-fifty homeobox
Arginine-fifty homeobox (ARGFX) is a protein
from Homo sapiens identified by UniProt accession
A6NJG6, 315 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Arginine-fifty homeobox |
|---|
| UniProt accession | A6NJG6 |
|---|
| Gene | ARGFX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 315 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.27
- breast carcinoma · score 0.04
- pancreatic adenocarcinoma · score 0.03
- arterial stiffness measurement · score 0.03
- cutaneous mastocytosis · score 0.02
- Stroke · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NJG6-F1 | alphafold | PREDICTED | 56.72 | — |
Amino-acid sequence (315 residues)
MRNRMAPENP QPDPFINRNY SNMKVIPPQD PASPSFTLLS KLECSGTVSA YCSLNLPGST DPPTSASRVA ATTAIRRRHK ERTSFTHQQY EELEALFSQT MFPDRNLQEK LALRLDLPES TVKVWFRNRR FKLKKQQQQQ SAKQRNQILP SKKNVPTSPR TSPSPYAFSP VISDFYSSLP SQPLDPSNWA WNSTFTESST SDFQMQDTQW ERLVASVPAL YSDAYDIFQI IELYNLPDEN EISSSSFHCL YQYLSPTKYQ VGGQGSSLSI FAGPAVGLSP AQTWPNMTSQ AFEAYSLTDS LEFQKTSNMV DLGFL
Explore Arginine-fifty homeobox with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets