About Zinc finger and SCAN domain-containing protein 5B
Zinc finger and SCAN domain-containing protein 5B (ZSCAN5B) is a protein
from Homo sapiens identified by UniProt accession
A6NJL1, 495 residues long.
MolForge cross-references it against 0 known binders and
57 disease associations.
Target properties
| Protein name | Zinc finger and SCAN domain-containing protein 5B |
|---|
| UniProt accession | A6NJL1 |
|---|
| Gene | ZSCAN5B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 495 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (57)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- early-onset non-syndromic cataract · score 0.07
- FRAXF syndrome · score 0.06
- Cataract-microcornea syndrome · score 0.06
- Total congenital cataract · score 0.06
- isolated ectopia lentis · score 0.06
- Cataract with Y-shaped suture opacities · score 0.05
- Anterior polar cataract · score 0.05
- Posterior polar cataract · score 0.05
- cataract · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NJL1-F1 | alphafold | PREDICTED | 58.28 | — |
Amino-acid sequence (495 residues)
MAANWTLSWG QGGPCNSPGS DTPRSVASPE TQLGNHDRNP ETWHMNFRMF SCPEESDPIQ ALRKLTELCH LWLRPDLHTK EQILDMLVME QFMISMPQEL QVLVKVNGVQ SCKDLEDLLR NNRRPKKWSI VNLLGKEYLM LNSDVEMAEA PASVRDDPRD VSSQWASSVN QMHPGTGQAR REQQILPRVA ALSRRQGEDF LLHKSIDVTG DPNSPRPKQT LEKDLKENRE ENPGLSSPEP QLPKSPNLVR AKEGKEPQKR ASVENVDADT PSACVVEREA LTHSGNRGDA LNLSSPKRSK PDASSISQEE PQGEATPVGN RESPGQAEIN PVHSPGPAGP VSHPDGQEAK ALPPFACDVC NKSFKYFSQL SIHRRSHTGD RPFQCDLCRK RFLQPSDLRV HQRVHTGERP YMCDVCQKRF AHESTLQGHK RIHTGERPFK CKYCSKVFSH KGNLNVHQRT HSGEKPYKCP TCQKAFRQLG TFKRHLKTHR ETTSQ
Explore Zinc finger and SCAN domain-containing protein 5B with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets