About Cis-aconitate decarboxylase
Cis-aconitate decarboxylase (ACOD1) is a protein
from Homo sapiens identified by UniProt accession
A6NK06, 481 residues long.
MolForge cross-references it against 0 known binders and
140 disease associations.
Target properties
| Protein name | Cis-aconitate decarboxylase |
|---|
| UniProt accession | A6NK06 |
|---|
| Gene | ACOD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 481 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (140)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.13
- neoplasm · score 0.11
- Obesity · score 0.09
- colitis · score 0.08
- hepatocellular carcinoma · score 0.08
- infect · score 0.08
- infection · score 0.08
- atherosclerosis · score 0.08
- Ischemic stroke · score 0.07
- cancer · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NK06-F1 | alphafold | PREDICTED | 95.21 | — |
Amino-acid sequence (481 residues)
MMLKSITESF ATAIHGLKVG HLTDRVIQRS KRMILDTLGA GFLGTTTEVF HIASQYSKIY SSNISSTVWG QPDIRLPPTY AAFVNGVAIH SMDFDDTWHP ATHPSGAVLP VLTALAEALP RSPKFSGLDL LLAFNVGIEV QGRLLHFAKE ANDMPKRFHP PSVVGTLGSA AAASKFLGLS STKCREALAI AVSHAGAPMA NAATQTKPLH IGNAAKHGIE AAFLAMLGLQ GNKQVLDLEA GFGAFYANYS PKVLPSIASY SWLLDQQDVA FKRFPAHLST HWVADAAASV RKHLVAERAL LPTDYIKRIV LRIPNVQYVN RPFPVSEHEA RHSFQYVACA MLLDGGITVP SFHECQINRP QVRELLSKVE LEYPPDNLPS FNILYCEISV TLKDGATFTD RSDTFYGHWR KPLSQEDLEE KFRANASKML SWDTVESLIK IVKNLEDLED CSVLTTLLKG PSPPEVASNS PACNNSITNL S
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