Zinc finger protein 98 (ZNF98)

About Zinc finger protein 98

Zinc finger protein 98 (ZNF98) is a protein from Homo sapiens identified by UniProt accession A6NK75, 572 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Zinc finger protein 98
UniProt accession	A6NK75
Gene	ZNF98
Organism	Homo sapiens
Length	572 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

Young adult-onset Parkinsonism · score 0.34
age at menopause · score 0.25
sitting height measurement · score 0.24
colorectal adenocarcinoma · score 0.04
adolescent idiopathic scoliosis · score 0.02
Down syndrome · score 0.01
acute lymphoblastic leukemia · score 0.01
acute myeloid leukemia · score 0.00
breast angiosarcoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NK75-F1	alphafold	PREDICTED	72.95	—

Amino-acid sequence (572 residues)

MPGPLGSLEM GVLTFRDVAL EFSLEEWQCL DTAQQNLYRN VMLENYRNLV FVGIAASKPD LITCLEQGKE PWNVKRHEMV TEPPVVYSYF AQDLWPKQGK KNYFQKVILR TYKKCGRENL QLRKYCKSMD ECKVHKECYN GLNQCLTTTQ NKIFQYDKYV KVFHKFSNSN RHKIGHTGKK SFKCKECEKS FCMLSHLAQH KRIHSGEKPY KCKECGKAYN EASNLSTHKR IHTGKKPYKC EECGKAFNRL SHLTTHKIIH TGKKPYKCEE CGKAFNQSAN LTTHKRIHTG EKPYKCEECG RAFSQSSTLT AHKIIHAGEK PYKCEECGKA FSQSSTLTTH KIIHTGEKFY KCEECGKAFS RLSHLTTHKR IHSGEKPYKC EECGKAFKQS STLTTHKRIH AGEKFYKCEV CSKAFSRFSH LTTHKRIHTG EKPYKCEECG KAFNLSSQLT THKIIHTGEK PYKCEECGKA FNQSSTLSKH KVIHTGEKPY KCEECGKAFN QSSHLTTHKM IHTGEKPYKC EECGKAFNNS SILNRHKMIH TGEKLYKPES CNNACDNIAK ISKYKRNCAG EK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards