About AT-rich interactive domain-containing protein 3C
AT-rich interactive domain-containing protein 3C (ARID3C) is a protein
from Homo sapiens identified by UniProt accession
A6NKF2, 412 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | AT-rich interactive domain-containing protein 3C |
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| UniProt accession | A6NKF2 |
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| Gene | ARID3C |
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| Organism | Homo sapiens |
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| Length | 412 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (18)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.22
- alkaline phosphatase measurement · score 0.18
- diastolic blood pressure · score 0.17
- hypertension · score 0.17
- aspartate aminotransferase measurement · score 0.15
- adolescent idiopathic scoliosis · score 0.15
- testosterone measurement · score 0.15
- neurodegenerative disease · score 0.13
- self reported educational attainment · score 0.11
- uterine disorder · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NKF2-F1 | alphafold | PREDICTED | 65.92 | — |
Amino-acid sequence (412 residues)
MEALQKQQAA RLAQGVGPLA PACPLLPPQP PLPDHRTLQA PEGALGNVGA EEEEDAEEDE EKREEAGAEE EAAEESRPGA QGPSSPSSQP PGLHPHEWTY EEQFKQLYEL DADPKRKEFL DDLFSFMQKR GTPVNRVPIM AKQVLDLYAL FRLVTAKGGL VEVINRKVWR EVTRGLSLPT TITSAAFTLR TQYMKYLYPY ECETRALSSP GELQAAIDSN RREGRRQAYT ATPLFGLAGP PPRGAQDPAL GPGPAPPATQ SSPGPAQGST SGLPAHACAQ LSPSPIKKEE SGIPNPCLAL PVGLALGPTR EKLAPEEPPE KRAVLMGPMD PPRPCMPPSF LPRGKVPLRE ERLDGPLNLA GSGISSINMA LEINGVVYTG VLFARRQPVP ASQGPTNPAP PPSTGPPSSI LP
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