Purkinje cell protein 4-like protein 1 (PCP4L1)

About Purkinje cell protein 4-like protein 1

Purkinje cell protein 4-like protein 1 (PCP4L1) is a protein from Homo sapiens identified by UniProt accession A6NKN8, 68 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Purkinje cell protein 4-like protein 1
UniProt accession	A6NKN8
Gene	PCP4L1
Organism	Homo sapiens
Length	68 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

prurigo · score 0.12
lichen disease · score 0.12
deafness · score 0.05
Red cell distribution width · score 0.05
glioblastoma multiforme · score 0.04
atypical teratoid rhabdoid tumor · score 0.04
Autosomal recessive spastic paraplegia type 44 · score 0.03
medulloblastoma · score 0.03
astrocytoma · score 0.03
central nervous system cancer · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NKN8-F1	alphafold	PREDICTED	71.46	—

Amino-acid sequence (68 residues)

MSELNTKTSP ATNQAAGQEE KGKAGNVKKA EEEEEIDIDL TAPETEKAAL AIQGKFRRFQ KRKKDPSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards