Cilia- and flagella-associated protein 144 (CFAP144)

About Cilia- and flagella-associated protein 144

Cilia- and flagella-associated protein 144 (CFAP144) is a protein from Homo sapiens identified by UniProt accession A6NL82, 134 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Cilia- and flagella-associated protein 144
UniProt accession	A6NL82
Gene	CFAP144
Organism	Homo sapiens
Length	134 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

adolescent idiopathic scoliosis · score 0.26
central nervous system cancer · score 0.04
Down syndrome · score 0.02
Intellectual disability · score 0.02
COVID-19 · score 0.01
ulcerative colitis · score 0.01
lung adenocarcinoma · score 0.01
endometrial carcinoma · score 0.00
neoplasm · score 0.00
Crohn's disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NL82-F1	alphafold	PREDICTED	79.31	—

Amino-acid sequence (134 residues)

MAGHPKEKVI PDEVHQNQIL RELYLKELRT QKLYTQYHVN PLRKIHTVTR KPMSWHDNLE EPADARFLNL IHHAAQGPRK KYPETQTENQ EVGWDLEPLI NPERHDRRLN HFRVCSDITL YKAKTWGLGD DHHK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards