About UPF0524 protein C3orf70
UPF0524 protein C3orf70 (C3orf70) is a protein
from Homo sapiens identified by UniProt accession
A6NLC5, 250 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | UPF0524 protein C3orf70 |
|---|
| UniProt accession | A6NLC5 |
|---|
| Gene | C3orf70 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 250 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.32
- unipolar depression · score 0.27
- self reported educational attainment · score 0.27
- mathematical ability · score 0.21
- drug use measurement · score 0.11
- anemia · score 0.11
- insomnia measurement · score 0.05
- pancreatic adenocarcinoma · score 0.04
- PHF-tau measurement · score 0.03
- congenital lipoid adrenal hyperplasia due to STAR deficency · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NLC5-F1 | alphafold | PREDICTED | 52.38 | — |
Amino-acid sequence (250 residues)
MSAAASPASE RGWKSEKLDE AQALARSCAA RRPDFQPCDG LSICATHSHG KCFKLHWCCH LGWCHCKYMY QPMTPVEQLP STEIPARPRE PTNTIQISVS LTEHFLKFAS VFQPPLPPDS PRYCMISDLF IDNYQVKCIN GKMCYVQKQP APHSHRMSPE EVSAHDALIS KESNTPKIDH CSSPSSSEDS GINAIGAHYV ESCDEDTEEG AELSSEEDYS PESSWEPDEC TLLSPSQSDL EVIETIETTV
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