About Tetratricopeptide repeat protein 36
Tetratricopeptide repeat protein 36 (TTC36) is a protein
from Homo sapiens identified by UniProt accession
A6NLP5, 189 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Tetratricopeptide repeat protein 36 |
|---|
| UniProt accession | A6NLP5 |
|---|
| Gene | TTC36 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 189 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.08
- sex hormone-binding globulin measurement · score 0.04
- chronic kidney disease · score 0.03
- apolipoprotein A 1 measurement · score 0.03
- metabolic syndrome · score 0.03
- body mass index · score 0.03
- high density lipoprotein cholesterol measurement · score 0.03
- psoriasis · score 0.03
- colorectal cancer · score 0.03
- Crohn's disease · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NLP5-F1 | alphafold | PREDICTED | 85.82 | — |
Amino-acid sequence (189 residues)
MGTPNDQAVL QAIFNPDTPF GDIVGLDLGE EAEKEEREED EVFPQAQLEQ SKALELQGVM AAEAGDLSTA LERFGQAICL LPERASAYNN RAQARRLQGD VAGALEDLER AVELSGGRGR AARQSFVQRG LLARLQGRDD DARRDFERAA RLGSPFARRQ LVLLNPYAAL CNRMLADMMG QLRRPRDSR
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