Zinc finger protein 92 homolog (ZFP92)

About Zinc finger protein 92 homolog

Zinc finger protein 92 homolog (ZFP92) is a protein from Homo sapiens identified by UniProt accession A6NM28, 416 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Zinc finger protein 92 homolog
UniProt accession	A6NM28
Gene	ZFP92
Organism	Homo sapiens
Length	416 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

early-onset non-syndromic cataract · score 0.10
hereditary hyperferritinemia with congenital cataracts · score 0.08
isolated ectopia lentis · score 0.08
Posterior polar cataract · score 0.08
Total congenital cataract · score 0.07
Cataract-microcornea syndrome · score 0.07
cataract 38 · score 0.07
cataract 13 with adult I phenotype · score 0.07
Anterior polar cataract · score 0.07
cataract · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NM28-F1	alphafold	PREDICTED	71.50	—

Amino-acid sequence (416 residues)

MAAILLTTRP KVPVSFEDVS VYFTKTEWKL LDLRQKVLYK RVMLENYSHL VSLGFSFSKP HLISQLERGE GPWVADIPRT WATAGLHIGD RTQSKTSTST QKHSGRQLPG ADPQGGKEGQ AARSSVLQRG AQGLGQSSAA GPQGPKGAEK RYLCQQCGKA FSRSSNLIKH RIIHSGEKPY ACPECGKLFR RSFALLEHQR IHSGEKPYAC PECSKTFTRS SNLIKHQVIH SGERPFACGD CGKLFRRSFA LLEHARVHSG ERPYACPECG KAFSRSSNLI EHQRTHRGEK PYACGQCAKA FKGVSQLIHH QRSHSGERPF ACRECGKAFR GRSGLSQHRR VHSGEKPYEC SDCGKAFGRR ANLFKHQAVH GARRPAKAET ARRLAGPGST GPGSAVAATS PPRPSTAARP SRPSRR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards