About Claudin-24
Claudin-24 (CLDN24) is a protein
from Homo sapiens identified by UniProt accession
A6NM45, 220 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Claudin-24 |
|---|
| UniProt accession | A6NM45 |
|---|
| Gene | CLDN24 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 220 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.34
- aspartate aminotransferase measurement · score 0.28
- body height · score 0.11
- heel bone mineral density · score 0.09
- red blood cell density measurement · score 0.08
- appendicular lean mass · score 0.07
- FEV/FVC ratio · score 0.07
- vital capacity · score 0.06
- sitting height measurement · score 0.06
- mean platelet volume · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NM45-F1 | alphafold | PREDICTED | 85.28 | — |
Amino-acid sequence (220 residues)
MALIFRTAMQ SVGLLLSLLG WILSIITTYL PHWKNLNLDL NEMENWTMGL WQTCVIQEEV GMQCKDFDSF LALPAELRVS RILMFLSNGL GFLGLLVSGF GLDCLRIGES QRDLKRRLLI LGGILSWASG ITALVPVSWV AHKTVQEFWD ENVPDFVPRW EFGEALFLGW FAGLSLLLGG CLLNCAACSS HAPLALGHYA VAQMQTQCPY LEDGTADPQV
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