About Fidgetin-like protein 2
Fidgetin-like protein 2 (FIGNL2) is a protein
from Homo sapiens identified by UniProt accession
A6NMB9, 653 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Fidgetin-like protein 2 |
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| UniProt accession | A6NMB9 |
|---|
| Gene | FIGNL2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 653 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.29
- energy intake measurement · score 0.28
- uric acid measurement · score 0.20
- erythrocyte count · score 0.06
- drug use measurement · score 0.02
- hepatocellular carcinoma · score 0.00
- chorea · score 0.00
- neoplasm · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NMB9-F1 | alphafold | PREDICTED | 60.35 | — |
Amino-acid sequence (653 residues)
MHWTPEHAQP LNQWPEQHLD VSSTTPSPAH KLELPPGGRQ RCHYAWAHDD ISALTASNLL KRYAEKYSGV LDSPYERPAL GGYSDASFLN GAKGDPEPWP GPEPPYPLAS LHEGLPGTKS GGGGGSGALG GSPVLAGNLP EPLYAGNACG GPSAAPEYAA GYGGGYLAPG YCAQTGAALP PPPPAALLQP PPPPGYGPSA PLYNYPAGGY AAQPGYGALP PPPGPPPAPY LTPGLPAPTP LPAPAPPTAY GFPTAAPGAE SGLSLKRKAA DEGPEGRYRK YAYEPAKAPV ADGASYPAAD NGECRGNGFR AKPPGAAEEA SGKYGGGVPL KVLGSPVYGP QLEPFEKFPE RAPAPRGGFA VPSGETPKGV DPGALELVTS KMVDCGPPVQ WADVAGQGAL KAALEEELVW PLLRPPAYPG SLRPPRTVLL FGPRGAGKAL LGRCLATQLG ATLLRLRGAT LAAPGAAEGA RLLQAAFAAA RCRPPSVLLI SELEALLPAR DDGAAAGGAL QVPLLACLDG GCGAGADGVL VVGTTSRPAA LDEATRRRFS LRFYVALPDS PARGQILQRA LAQQGCALSE RELAALVQGT QGFSGGELGQ LCQQAAAGAG LPGLQRPLSY KDLEAALAKV GPRASAKELD SFVEWDKMYG SGH
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