Interferon-induced transmembrane protein 10 (IFITM10)

Homo sapiens — UniProt A6NMD0

Gene: IFITM10Homo sapiensSwissProt reviewed

About Interferon-induced transmembrane protein 10

Interferon-induced transmembrane protein 10 (IFITM10) is a protein from Homo sapiens identified by UniProt accession A6NMD0, 228 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein nameInterferon-induced transmembrane protein 10
UniProt accessionA6NMD0
GeneIFITM10
OrganismHomo sapiens
Length228 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (28)

Diseases linked to this target (Open Targets).

  • cathepsin D measurement · score 0.31
  • blood protein measurement · score 0.29
  • biliary tract disease · score 0.23
  • pancreas disease · score 0.23
  • gallbladder disease · score 0.23
  • Abnormality of refraction · score 0.10
  • aspartate aminotransferase measurement · score 0.07
  • gonorrhea · score 0.05
  • neoplasm · score 0.03
  • hepatocellular carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NMD0-F1alphafoldPREDICTED54.58—

Amino-acid sequence (228 residues)

MREGKRGPPC ILSFRGTLER VEAQWELEAQ GPGQCPAPLG DPASTTDGAQ EARVPLDGAF WIPRPPAGSP KGCFACVSKP PALQAPAAPA PEPSASPPMA PTLFPMESKS SKTDSVRAAG APPACKHLAE KKTMTNPTTV IEVYPDTTEV NDYYLWSIFN FVYLNFCCLG FIALAYSLKV RDKKLLNDLN GAVEDAKTAR LFNITSSALA ASCIILVFIF LRYPLTDY

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Quick facts

UniProtA6NMD0
GeneIFITM10
OrganismHomo sapiens
Length228
Binders0
Diseases28
View on UniProt