About Interferon-induced transmembrane protein 10
Interferon-induced transmembrane protein 10 (IFITM10) is a protein
from Homo sapiens identified by UniProt accession
A6NMD0, 228 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Interferon-induced transmembrane protein 10 |
| UniProt accession | A6NMD0 |
| Gene | IFITM10 |
| Organism | Homo sapiens |
| Length | 228 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- cathepsin D measurement · score 0.31
- blood protein measurement · score 0.29
- biliary tract disease · score 0.23
- pancreas disease · score 0.23
- gallbladder disease · score 0.23
- Abnormality of refraction · score 0.10
- aspartate aminotransferase measurement · score 0.07
- gonorrhea · score 0.05
- neoplasm · score 0.03
- hepatocellular carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-A6NMD0-F1 | alphafold | PREDICTED | 54.58 | — |
Amino-acid sequence (228 residues)
MREGKRGPPC ILSFRGTLER VEAQWELEAQ GPGQCPAPLG DPASTTDGAQ EARVPLDGAF WIPRPPAGSP KGCFACVSKP PALQAPAAPA PEPSASPPMA PTLFPMESKS SKTDSVRAAG APPACKHLAE KKTMTNPTTV IEVYPDTTEV NDYYLWSIFN FVYLNFCCLG FIALAYSLKV RDKKLLNDLN GAVEDAKTAR LFNITSSALA ASCIILVFIF LRYPLTDY
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