About Uncharacterized protein C2orf81
Uncharacterized protein C2orf81 (C2orf81) is a protein
from Homo sapiens identified by UniProt accession
A6NN90, 582 residues long.
MolForge cross-references it against 0 known binders and
2 disease associations.
Target properties
| Protein name | Uncharacterized protein C2orf81 |
|---|
| UniProt accession | A6NN90 |
|---|
| Gene | C2orf81 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 582 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (2)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- Stress urinary incontinence · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NN90-F1 | alphafold | PREDICTED | 51.20 | — |
Amino-acid sequence (582 residues)
MAHEGSRQVR DRGVTRSKAE KVRPPTVPVP QVDIVPGRLS EAEWMALTAL EEGEDVVGDI LADLLARVMD SAFKVYLTQQ CIPFTISQAR EAMLQITEWR FLARDEGESA VAEDPTWGED EEPSACTTDS WAQGSVPVLH ASTSEGLENF QGEDPGGVDR IPLGRSWMGR GSQEQMESWE PSPQLRVTSA PPPTSELFQE AGPGGPVEEA DGQSRGLSSA GSLSASFQLS VEEAPADDAD PSLDPYLVAS PQASTGRGHP LGFHLSLEDL YCCMPQLDAA GDRLELRSEG VPCIASGVLV SYPSVGGATR PSASCQQQRA GHSDVRLSAH HHRMRRKAAV KRLDPARLPC HWVRPLAEVL VPDSQTRPLE AYRGRQRGEK TKARAEPQAL GPGTRVSPAA FFPLRPGIPF RDLDSGPALL FPTLNLGLSS PSLESKLPLP NSRIRFLTTH PVLPDVARSR SPKLWPSVRW PSGWEGKAEL LGELWAGRTR VPPQGLELAD REGQDPGRWP RTTPPVLEAT SQVMWKPVLL PEALKLAPGV SMWNRSTQVL LSSGVPEQED KEGSTFPPVE QHPIQTGAPK PR
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