About Olfactory receptor 2AT4
Olfactory receptor 2AT4 (OR2AT4) is a protein
from Homo sapiens identified by UniProt accession
A6NND4, 320 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Olfactory receptor 2AT4 |
|---|
| UniProt accession | A6NND4 |
|---|
| Gene | OR2AT4 |
|---|
| Organism | Homo sapiens |
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| Length | 320 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- visual perception measurement · score 0.03
- breast carcinoma · score 0.01
- cancer · score 0.01
- myeloid leukemia · score 0.01
- non-small cell lung carcinoma · score 0.01
- neoplasm · score 0.01
- acute myeloid leukemia · score 0.01
- chronic myelogenous leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NND4-F1 | alphafold | PREDICTED | 89.80 | — |
Amino-acid sequence (320 residues)
MDATACNESV DGSPVFYLLG IPSLPETFFL PVFFIFLLFY LLILMGNALI LVAVVAEPSL HKPMYFFLIN LSTLDILFTT TTVPKMLSLF LLGDRFLSFS SCLLQMYLFQ SFTCSEAFIL VVMAYDRYVA ICHPLHYPVL MNPQTNATLA ASAWLTALLL PIPAVVRTSQ MAYNSIAYIY HCFCDHLAVV QASCSDTTPQ TLMGFCIAMV VSFLPLLLVL LSYVHILASV LRISSLEGRA KAFSTCSSHL LVVGTYYSSI AIAYVAYRAD LPLDFHIMGN VVYAILTPIL NPLIYTLRNR DVKAAITKIM SQDPGCDRSI
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