Zinc finger protein 716 (ZNF716)

About Zinc finger protein 716

Zinc finger protein 716 (ZNF716) is a protein from Homo sapiens identified by UniProt accession A6NP11, 495 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Zinc finger protein 716
UniProt accession	A6NP11
Gene	ZNF716
Organism	Homo sapiens
Length	495 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

nasopharyngeal neoplasm · score 0.27
retinitis pigmentosa · score 0.07
injury · score 0.06
Leber congenital amaurosis · score 0.05
aniridia · score 0.05
Aniridia-intellectual disability syndrome · score 0.04
Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
congenital glaucoma · score 0.04
retinitis pigmentosa 71 · score 0.04
isolated optic nerve hypoplasia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NP11-F1	alphafold	PREDICTED	70.77	—

Amino-acid sequence (495 residues)

MAKRPGPPGS REMGLLTFRD IAIEFSLAEW QCLDHAQQNL YRDVMLENYR NLVSLGIAVS KPDLITCLEQ NKEPQNIKRN EMVAKHPVTC SHFTQDLQSE QGIKDSLQKV ILRRYGKCGQ EDLQVKKCCK SVGECEVHKG GYNYVNQCLS ATQNKTFQTH KCVKVFGKFS NSNRHKTRHT GKKHFKCKND GKSFCMLSRL NQHQIIHTRE KSYKCEECGK SFNCSSTLTR HKRIHTGEKP YRCEECGKAF SWSASLTKHK RIHTGEKPYT CEERGKVFSR STLTNYKRIH TGEKPYTCEE CGKAFSRSST LTNHKRIHTG ERPYKCEECG KAFSLSSTLK KHKIVHTGEK LYTCEECGKA FTFSSTLNTH KRIHTGEKPY TCEECGKAFS LPSTFTYHKR THTGEKPYKC EECGKAFNCS STLKKHKIIH TGEKLYKCKE CGKAFTFSST LNTHKRIHTG EKPYKCEECD QTFKWHSSLA NHKNMHTGEK PYKYE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards