Protein ZAR1-like (ZAR1L)

About Protein ZAR1-like

Protein ZAR1-like (ZAR1L) is a protein from Homo sapiens identified by UniProt accession A6NP61, 321 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Protein ZAR1-like
UniProt accession	A6NP61
Gene	ZAR1L
Organism	Homo sapiens
Length	321 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

Hereditary breast and ovarian cancer syndrome · score 0.37
hereditary breast ovarian cancer syndrome · score 0.36
neurodegenerative disease · score 0.16
low density lipoprotein cholesterol measurement · score 0.11
mean platelet volume · score 0.09
platelet count · score 0.09
schizophrenia · score 0.07
anti-chlamydia trachomatis antibody measurement · score 0.06
apolipoprotein B measurement · score 0.06
body height · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NP61-F1	alphafold	PREDICTED	58.07	—

Amino-acid sequence (321 residues)

MERFVRVPYG LYQGYGSTVP LGQPGLSGHK QPDWRQNMGP PTFLARPGLL VPANAPDYCI DPYKRAQLKA ILSQMNPSLS PRLCKPNTKE VGVQVSPRVD KAVQCSLGPR TLSSCSPWDG RDPQEPLPAC GVTSPATGRR GLIRLRRDGD EAESKALPGP AEASQPQPPS RRSGADRQEE PGQLEESGEK DAPCPQETKS KQVPGDAASE PLRRPNFQFL EPKYGYFHCK DCKTRWESAY VWCISGTNKV YFKQLCCKCQ KSFNPYRVEA IQCQTCSKSH CSCPQKKRHI DLRRPHRQEL CGRCKDKRFS CGNIYSFKYV M

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards