Nuclear cap-binding protein subunit 2-like (NCBP2L)

About Nuclear cap-binding protein subunit 2-like

Nuclear cap-binding protein subunit 2-like (NCBP2L) is a protein from Homo sapiens identified by UniProt accession A6PVI3, 153 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Nuclear cap-binding protein subunit 2-like
UniProt accession	A6PVI3
Gene	NCBP2L
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

major depressive disorder · score 0.07
obsessive-compulsive disorder · score 0.06
neoplasm · score 0.01
Crohn's disease · score 0.00
ulcerative colitis · score 0.00
systemic juvenile idiopathic arthritis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6PVI3-F1	alphafold	PREDICTED	94.89	—

Amino-acid sequence (153 residues)

MSKDLKILCK DPALELSCYR DHQFSGRKFQ QEKLLKESST LNMGNLSFYT TEEKIHELFS RSDIRNIFMG LDKIKKTACG FCFVECHNRA DAENAMRFLT GTCLDEWIIC TDWDVGFREG QQYGRGKSGG QVRDEFREDF HSGRGGFGRQ TQI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards