YjeF N-terminal domain-containing protein 3 (YJEFN3)

About YjeF N-terminal domain-containing protein 3

YjeF N-terminal domain-containing protein 3 (YJEFN3) is a protein from Homo sapiens identified by UniProt accession A6XGL0, 299 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.

Target properties

Protein name	YjeF N-terminal domain-containing protein 3
UniProt accession	A6XGL0
Gene	YJEFN3
Organism	Homo sapiens
Length	299 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (76)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.40
basophil count · score 0.14
Red cell distribution width · score 0.12
monocyte count · score 0.10
bipolar disorder · score 0.10
eosinophil count · score 0.09
breast carcinoma · score 0.08
body height · score 0.08
body mass index · score 0.08
platelet count · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6XGL0-F1	alphafold	PREDICTED	82.40	—

Amino-acid sequence (299 residues)

MSSAAGPDPS EAPEERHFLR ALELQPPLAD MGRAELSSNA TTSLVQRRKQ AWGRQSWLEQ IWNAGPVCQS TAEAAALERE LLEDYRFGRQ QLVELCGHAS AVAVTKAFPL PALSRKQRTV LVVCGPEQNG AVGLVCARHL RVFEYEPTIF YPTRSLDLLH RDLTTQCEKM DIPFLSYLPT EVQLINEAYG LVVDAVLGPG VEPGEVGGPC TRALATLKLL SIPLVSLDIP SGWDAETGSD SEDGLRPDVL VSLAAPKRCA GRFSGRHHFV AGRFVPDDVR RKFALRLPGY TGTDCVAAL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards