Cilia-and flagella-associated protein 96 (CFAP96)

About Cilia-and flagella-associated protein 96

Cilia-and flagella-associated protein 96 (CFAP96) is a protein from Homo sapiens identified by UniProt accession A7E2U8, 309 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Cilia-and flagella-associated protein 96
UniProt accession	A7E2U8
Gene	CFAP96
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

systemic scleroderma · score 0.05
ependymoma · score 0.03
cancer · score 0.03
clear cell renal carcinoma · score 0.03
smoking behaviour measurement · score 0.02
childhood trauma measurement · score 0.02
gallbladder carcinoma · score 0.01
Keloid · score 0.01
neoplasm · score 0.01
papillary thyroid carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A7E2U8-F1	alphafold	PREDICTED	73.85	—

Amino-acid sequence (309 residues)

MPAEGGKTDM ERIGLFSEME YITVGDKYVS QFNRPFNEAA SKNKQMLPGG SKEMSDLQAG YFDPHFVRIF EGEGYINLNQ VRRRDMVEAA KKNLGKAFLP SNGEKKPCGL GSYYGTIGGP VPFFSAQSKP REKYKAPGKN LYTNPGKKGT GYGYANITIG KQFSHSADFY DAAKLKYKKA NEEHHRLLKG APFKLNLHPR DYFDANPYFS EESLPPIKKE EKKKTISNTF KPSSPGKKPG GMKAGTFDPY PSHSADPYVA KLANISGKDD KIFHPPSGPK SRPVESIMTL NVRRALNSKN YKTSSVPSY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards