About Zinc finger protein 891
Zinc finger protein 891 (ZNF891) is a protein
from Homo sapiens identified by UniProt accession
A8MT65, 544 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Zinc finger protein 891 |
|---|
| UniProt accession | A8MT65 |
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| Gene | ZNF891 |
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| Organism | Homo sapiens |
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| Length | 544 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.21
- Abnormality of refraction · score 0.20
- type 2 diabetes mellitus · score 0.16
- cortical thickness · score 0.15
- brain measurement · score 0.12
- cortical surface area measurement · score 0.12
- intraocular pressure measurement · score 0.12
- mean corpuscular hemoglobin concentration · score 0.10
- platelet count · score 0.07
- mean platelet volume · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MT65-F1 | alphafold | PREDICTED | 56.45 | — |
Amino-acid sequence (544 residues)
MAVMDLSSPW ALTKQDSACF HLRNAEEERM IAVFLTTWLQ EPMTFKDVAV EFTQEEWMML DSAQRSLYRD VMLENYRNLT SVEYQLYRLT VISPLDQEEI RNMKKRIPQA ICPDQKIQPK TKESTVQKIL WEEPSNAVKM IKLTMHNWSS TLREDWECHK IRKQHKIPGG HWRQMIYAPK KTVPQELFRD YHELEENSKL GSKLIFSQSI FTSKHCQKCY SEIGCLKHNS IINNYVKNSI SEKLYESHEC DTTLWHFQRN QTVQKEYTYS KHGMHFTHNM FPVPNNLHMA QNACECNKDE TLCHQSSLKK QGQTHTEKKH ECNQCGKAFK RISNLTLYKK SHMGEKQYEC KECGKVFNDS STLRRHVRTH TGEKPYECNQ CGKAFSQKTS LKAHMRTHTG EKPYECNQCG KSFGTSSYLI VHKRIHTGEK LYECSECGKA FNTSSHLKVH KKIHTGENVY ECSDCGKVFS GVSSLRMHIR THTGEKPYEC KECRKAFSVS SSLRRHVRIH TGEKPYECIQ CGKAFSQSSS LIIHKRIHTE RETL
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