About Cell adhesion molecule CEACAM18
Cell adhesion molecule CEACAM18 (CEACAM18) is a protein
from Homo sapiens identified by UniProt accession
A8MTB9, 384 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Cell adhesion molecule CEACAM18 |
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| UniProt accession | A8MTB9 |
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| Gene | CEACAM18 |
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| Organism | Homo sapiens |
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| Length | 384 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (5)
Diseases linked to this target (Open Targets).
- Barrett's esophagus · score 0.06
- Crohn's disease · score 0.04
- sessile serrated polyp · score 0.01
- Colon Sessile Serrated Adenoma/Polyp · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MTB9-F1 | alphafold | PREDICTED | 79.86 | — |
Amino-acid sequence (384 residues)
MDLSRPRWSL WRRVFLMASL LACGICQASG QIFITQTLGI KGYRTVVALD KVPEDVQEYS WYWGANDSAG NMIISHKPPS AQQPGPMYTG RERVNREGSL LIRPTALNDT GNYTVRVVAG NETQRATGWL EVLELGSNLG ISVNASSLVE NMDSVAADCL TNVTNITWYV NDVPTSSSDR MTISPDGKTL VILRVSRYDR TIQCMIESFP EIFQRSERIS LTVAYGPDYV LLRSNPDDFN GIVTAEIGSQ VEMECICYSF LDLKYHWIHN GSLLNFSDAK MNLSSLAWEQ MGRYRCTVEN PVTQLIMYMD VRIQAPHEDL TCCPQRFLHL RIHGDVPHHA DSAGWRLHLW SPDPCSDQPL LNQDKSGSMS VHPRPEDKTR RASR
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