IQ domain-containing protein F5 (IQCF5)

About IQ domain-containing protein F5

IQ domain-containing protein F5 (IQCF5) is a protein from Homo sapiens identified by UniProt accession A8MTL0, 148 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	IQ domain-containing protein F5
UniProt accession	A8MTL0
Gene	IQCF5
Organism	Homo sapiens
Length	148 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.24
sporadic amyotrophic lateral sclerosis · score 0.15
Aganglionic megacolon · score 0.11
Hirschsprung disease · score 0.11
Abnormal sperm morphology · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MTL0-F1	alphafold	PREDICTED	92.88	—

Amino-acid sequence (148 residues)

MGPEEKTIMT ERSAAVFIQA WWRGMLVRRT LLHAALRAWI IQCWWRQVLE KLLAKRRRMV LEFYVQQEWA AVRLQSWVRM WCVRQRYCRL LNAVRIIQVY WRWHSCHSRV FIEGHYELKE NQLNIQLEIS LGLQACKVQQ CIPLPLKE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards