About Uncharacterized protein C12orf71
Uncharacterized protein C12orf71 (C12orf71) is a protein
from Homo sapiens identified by UniProt accession
A8MTZ7, 269 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Uncharacterized protein C12orf71 |
|---|
| UniProt accession | A8MTZ7 |
|---|
| Gene | C12orf71 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 269 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.39
- self reported educational attainment · score 0.33
- diastolic blood pressure · score 0.18
- mathematical ability · score 0.17
- blood pressure · score 0.14
- adolescent idiopathic scoliosis · score 0.08
- protein measurement · score 0.07
- pancreatic adenocarcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MTZ7-F1 | alphafold | PREDICTED | 53.15 | — |
Amino-acid sequence (269 residues)
MAYSSSNSDI EDDSSKSNSN LSLSVGYFPC EDTPCEDTTS WEDAPSKGPS IHFLPPVQGA WGTERIGRRM KRQDQIQDEP EQFCKLSIFL AWDVDIGSDN TDSRANRLLN GDNLWIDKLP KERTKLSVGK LNNLVQEFQI FLENLKDDDA VFPETAQQDF QLSSGSPPEM VQMISQATAS QRTSAPEISS ILSEQPEKDD TPSHTQAQCC LNFGWAFSWL RQRILPSLLR RDHPVNATKS PHRSAPTKRL FHRGKRIQPQ ETLELGHPI
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