Germ cell-specific gene 1-like protein 2 (GSG1L2)

About Germ cell-specific gene 1-like protein 2

Germ cell-specific gene 1-like protein 2 (GSG1L2) is a protein from Homo sapiens identified by UniProt accession A8MUP6, 293 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Germ cell-specific gene 1-like protein 2
UniProt accession	A8MUP6
Gene	GSG1L2
Organism	Homo sapiens
Length	293 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

venous thromboembolism · score 0.26
metabolite measurement · score 0.05
non-small cell lung carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MUP6-F1	alphafold	PREDICTED	75.61	—

Amino-acid sequence (293 residues)

MDRAKQQQAL LLLPVCLALT FSLTAVVSSH WCEGTRRVVK PLCQDQPGGQ HCIHFKRDNS SNGRMDNNSQ AVLYIWELGD DKFIQRGFHV GLWQSCEESL NGEDEKCRSF RSVVPAEEQG VLWLSIGGEV LDIVLILTSA ILLGSRVSCR SPGFHWLRVD ALVAIFMVLA GLLGMVAHMM YTTIFQITVN LGPEDWKPQT WDYGWSYCLA WGSFALCLAV SVSAMSRFTA ARLEFTEKQQ AQNGSRHSQH SFLEPEASES IWKTGAAPCP AEQAFRNVSG HLPPGAPGKV SIC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards