Melanoma-associated antigen B17 (MAGEB17)

About Melanoma-associated antigen B17

Melanoma-associated antigen B17 (MAGEB17) is a protein from Homo sapiens identified by UniProt accession A8MXT2, 336 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Melanoma-associated antigen B17
UniProt accession	A8MXT2
Gene	MAGEB17
Organism	Homo sapiens
Length	336 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

Down syndrome · score 0.03
colorectal cancer · score 0.01
neoplasm · score 0.00
prostate carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MXT2-F1	alphafold	PREDICTED	73.76	—

Amino-acid sequence (336 residues)

MPRGQASKRR AREKRRQARG EDQCLGGAQA TAAEKEKLPS SSSPACQSPP QSFPNAGIPQ ESQRASYPSS PASAVSLTSS DEGAKGQKGE SPNSFHGPSS SESTGRDLLN TKTGELVQFL LNKYIRKEPI TREAMLKVIN RKYKQHFPEI LRRSTENVEV VFGLYLKEMD PSRQSYVLVG KLDFPNQGSL SDGGGFPLSG LLMVLLSTIF MHGNRATEEE MWECLNALGM YKGRKHFIYG EPQELVTKDL VREGYLEYQQ VPSSDPPRYE FLWGPRARAE TSKMKVLEFV AKLNDTVAST YKSRYEEALR EEEEQARARA VARDSARARA SRSFQP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards