Acyl-coenzyme A diphosphatase NUDT19 (NUDT19)

About Acyl-coenzyme A diphosphatase NUDT19

Acyl-coenzyme A diphosphatase NUDT19 (NUDT19) is a protein from Homo sapiens identified by UniProt accession A8MXV4, 375 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Acyl-coenzyme A diphosphatase NUDT19
UniProt accession	A8MXV4
Gene	NUDT19
Organism	Homo sapiens
Length	375 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

creatinine measurement · score 0.22
hemoglobin measurement · score 0.22
cystatin C measurement · score 0.17
mean corpuscular volume · score 0.16
urinary metabolite measurement · score 0.13
genetic disorder · score 0.12
mean corpuscular hemoglobin concentration · score 0.07
Red cell distribution width · score 0.04
bleeding disorder, platelet-type, 24 · score 0.03
platelet-type bleeding disorder 15 · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MXV4-F1	alphafold	PREDICTED	87.80	—

Amino-acid sequence (375 residues)

MSSSLRPGPS RWRRAASIVL AAGWSRPETA TPPSRPPPAE GFRLLLLQRS PHQGFMPGAH VFSGGVLDAA DRSADWLGLF APHHGPPRFG LGPAPFSRTA FPSLPDTDDH KTDNTGTLPE DVAFRICAVR EAFEEAGVLL LRPRTSPPGP APGPGLALEP PPGLASWRDR VRQDPRHFLR LCAHLDCTPD IWALHNWSAW LTPFLRGTTR RFDTAFFLCC LREPPPVYPD LAEVVGYQWS SPSEATESFL SKEIWLPPPQ FYEVRRLANF ASLSDLHKFC LGRALEGLER WLPIILLTAD GMVHLLPGDE LYLEDSDFLE NLMSTEKKTE EIMKEGKQFH RIVTYHRHLY DIHVTVQPKY KHVYPKNSVV RKSHL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards