About CMT1A duplicated region transcript 15 protein-like protein
CMT1A duplicated region transcript 15 protein-like protein (CDRT15L2) is a protein
from Homo sapiens identified by UniProt accession
A8MXV6, 281 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | CMT1A duplicated region transcript 15 protein-like protein |
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| UniProt accession | A8MXV6 |
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| Gene | CDRT15L2 |
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| Organism | Homo sapiens |
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| Length | 281 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- breast disease · score 0.25
- mean platelet volume · score 0.09
- mean corpuscular hemoglobin · score 0.02
- reticulocyte measurement · score 0.02
- mean corpuscular hemoglobin concentration · score 0.02
- mean reticulocyte volume · score 0.02
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MXV6-F1 | alphafold | PREDICTED | 54.36 | — |
Amino-acid sequence (281 residues)
MFSCCFPTSR GCCFRNGGSE SLFRQCRRRL IPHPRRLWPF VRRRTQVPQD SPGQALAGQA TPEIPSGLPL HIVLVQEEIR EPMEAQTHAP GPYADIAALA APAVEPKPAW EEPPPERALE VEGAPAKDQP SQELPEIMAP TVATGLNAGA ENVAGERSGR EGVTSTAPAS RSHAAPSPGH GGKHGGGDQG IQTGLLYLAG ERLLSFAGTT ALLLQGLFIV LILVGYISVK VMLKSIKTRL GRRVPAAPPA LRRNLLLQAW KCVCNWASRL FAPNVLPRTG S
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