Keratin-associated protein 9-1 (KRTAP9-1)

About Keratin-associated protein 9-1

Keratin-associated protein 9-1 (KRTAP9-1) is a protein from Homo sapiens identified by UniProt accession A8MXZ3, 250 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Keratin-associated protein 9-1
UniProt accession	A8MXZ3
Gene	KRTAP9-1
Organism	Homo sapiens
Length	250 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

Hypomaturation amelogenesis imperfecta · score 0.06
amelogenesis imperfecta · score 0.05
Hypoplastic amelogenesis imperfecta · score 0.05
amelogenesis imperfecta type 1G · score 0.05
tooth agenesis · score 0.04
dentin dysplasia type I · score 0.04
kidney disease · score 0.04
amelogenesis imperfecta, type ij · score 0.04
dentinogenesis imperfecta · score 0.04
hepatorenocardiac degenerative fibrosis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MXZ3-F1	alphafold	PREDICTED	35.36	—

Amino-acid sequence (250 residues)

MTHCCSPCCQ PTCCRTTCCR TTCWKPTTVT TCSSTPCCQP SCCVPSCCQP CCHPTCCQNT CCRTTCCQPT CVASCCQPSC CSTPCCQPTC CGSSCCGQTS CGSSCCQPIC GSSCCQPCCH PTCYQTICFR TTCCQPTCCQ PTCCRNTSCQ PTCCGSSCCQ PCCHPTCCQT ICRSTCCQPS CVTRCCSTPC CQPTCGGSSC CSQTCNESSY CLPCCRPTCC QTTCYRTTCC RPSCCCSPCC VSSCCQPSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards