About Uncharacterized protein CXorf49
Uncharacterized protein CXorf49 (CXorf49) is a protein
from Homo sapiens identified by UniProt accession
A8MYA2, 514 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | Uncharacterized protein CXorf49 |
|---|
| UniProt accession | A8MYA2 |
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| Gene | CXorf49 |
|---|
| Organism | Homo sapiens |
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| Length | 514 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (3)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.02
- Azoospermia · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MYA2-F1 | alphafold | PREDICTED | 49.53 | — |
Amino-acid sequence (514 residues)
MSSPDKVSVC GAGFDLEGGK KAGSRTASPG APGAHSHGLD LGVPGSGDGK SESGFTDPEG FSFESESELI EQGRVVLWGR EGRPGTPVDD QGDVVDYSFY LADEPAAIVP PPSVQGHPFP EGAAAEGSAE NWADAEVGPS GRDVLGHSPG KWQQASAGRL HLCGPGPVRA WKNPERGSKS RWSLRVDPQQ PSAKGPTRLP THDSDSADES SDLPLMKVGI CRNEGSQAKP GSPKKRADTS RQASFHCKES YLPVPGRFLT SAPRGLTPVA ERPAVGELED SPQKKMQSRA WGKVEVRPSC SGAAAAGALP QGLSRRKMAG GKKSLGGASQ LALGRGFPAC GERLSAAPPE PATFPPFSGV RPQGMSKKPQ KPKHSSPGKK PAGRKTRESQ AAAREDNDPN RDEVPRAQLP THRPGLPRLS VRRGEFSSSD PNIRAPQLPG TSEPSAYSPG GLVPRRHAPS GNQQPPVHPP RPERQQQPPG AQGCPRCIWL QREIEDLTQQ LAAMQFLTDK FQDL
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