Ciliary microtubule associated protein 1B (CIMAP1B)

About Ciliary microtubule associated protein 1B

Ciliary microtubule associated protein 1B (CIMAP1B) is a protein from Homo sapiens identified by UniProt accession A8MYP8, 253 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name	Ciliary microtubule associated protein 1B
UniProt accession	A8MYP8
Gene	CIMAP1B
Organism	Homo sapiens
Length	253 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (62)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.24
mean corpuscular hemoglobin · score 0.24
erythrocyte count · score 0.23
reticulocyte count · score 0.22
mean corpuscular hemoglobin concentration · score 0.21
red blood cell density measurement · score 0.20
multiple sclerosis · score 0.19
reticulocyte measurement · score 0.18
monocyte percentage of leukocytes · score 0.17
mean reticulocyte volume · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MYP8-F1	alphafold	PREDICTED	74.00	—

Amino-acid sequence (253 residues)

MGSDAWVGLW RPHRPRGPIA AHYGGPGPKY KLPPNTGYAL HDPSRPRAPA FTFGARFPTQ QTTCGPGPGH LVPARMTVRG TDGAPAYSIY GRPRRSAPFL TPGPGRYFPE RAGNATYPSA PRHTIAPRNW GVQAEQQSPG PAAYTVPSLL GPRVIGKVSA PTCSIYGRRA AGSFFEDLSK TPGPCAYQVV SPGVYKSRAP QFTILARTSL PQDNTRKPGP AAYNVDQHRK PRGWSFGIRH SDYLAPLVTD ADN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards