About Envoplakin-like protein
Envoplakin-like protein (EVPLL) is a protein
from Homo sapiens identified by UniProt accession
A8MZ36, 301 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Envoplakin-like protein |
|---|
| UniProt accession | A8MZ36 |
|---|
| Gene | EVPLL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 301 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.26
- body height · score 0.14
- IGF-1 measurement · score 0.05
- multiple sclerosis · score 0.04
- blood protein measurement · score 0.02
- serum alanine aminotransferase measurement · score 0.02
- ulcerative colitis · score 0.01
- Crohn's disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MZ36-F1 | alphafold | PREDICTED | 67.97 | — |
Amino-acid sequence (301 residues)
MQASADQVER DILETQKRLQ QDRLNSEQSQ ALQHQQETGS SLKEAEVLLK DLFLDVDKAR RLKHPQAEET EKDIEQLHER VTQECAEYCA LYEKMVLPPR RGIQGRLGTR AGAETEAGLR RPVWAGHGGA GGTDRGAQHR AEGDQRPRRA AAEPGGAGCR HHPEPIPRPT EGGVVARAEP GQPVHALQGC TWQLSALAEQ QRRILQQDWS DLMADPAGVR REYEHFKQHE LLSQEQSVNQ LEEDGKRMVE LRHPAVGPIQ AHQEALKMEW QNFLNLCICQ ETQLQHVEDY SRILCPSSSP H
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