About Uncharacterized protein C2orf74
Uncharacterized protein C2orf74 (C2orf74) is a protein
from Homo sapiens identified by UniProt accession
A8MZ97, 187 residues long.
MolForge cross-references it against 0 known binders and
64 disease associations.
Target properties
| Protein name | Uncharacterized protein C2orf74 |
|---|
| UniProt accession | A8MZ97 |
|---|
| Gene | C2orf74 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 187 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (64)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.32
- neuroticism measurement · score 0.29
- Immature Reticulocyte Fraction Measurement · score 0.19
- reticulocyte count · score 0.16
- body height · score 0.14
- mean corpuscular hemoglobin concentration · score 0.11
- alkaline phosphatase measurement · score 0.10
- reticulocyte measurement · score 0.10
- vital capacity · score 0.10
- self reported educational attainment · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MZ97-F1 | alphafold | PREDICTED | 58.16 | — |
Amino-acid sequence (187 residues)
MSFETTAITF FIILLICLIC ILLLLVVFLY KCFQGRKGKE TKKVPCTDAN GGVDCAAAKV VTSNPEDHER ILMQVMNLNV PMRPGILVQR QSKEVLATPL ENRRDMEAEE ENQINEKQEP ENAGETGQEE DDGLQKIHTS VTRTPSVVES QKRPLKGVTF SREVIVVDLG NEYPTPRSYT REHKERK
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