About Uncharacterized protein C16orf90
Uncharacterized protein C16orf90 (C16orf90) is a protein
from Homo sapiens identified by UniProt accession
A8MZG2, 182 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Uncharacterized protein C16orf90 |
| UniProt accession | A8MZG2 |
| Gene | C16orf90 |
| Organism | Homo sapiens |
| Length | 182 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- serum gamma-glutamyl transferase measurement · score 0.24
- systolic blood pressure · score 0.08
- eosinophil count · score 0.08
- sunburn · score 0.07
- eosinophil percentage of leukocytes · score 0.05
- vital capacity · score 0.05
- lymphocyte percentage of leukocytes · score 0.03
- diastolic blood pressure · score 0.03
- creatinine measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-A8MZG2-F1 | alphafold | PREDICTED | 54.16 | — |
Amino-acid sequence (182 residues)
MEALVCAFSE LHIREDAVSQ AQGRPGHPDA PPNIYEGGLG SPQPQCPSAQ GSKPKNFRLR HLRGLGLYLE SHPPPTGQCE SHWLGRLMAG GCLPQPEGTA WALDLPQGTL GPRNSLCSAL LEARLPRDSL GSSASSSSMD PDKGALPQPS PSRLRPKRSW GTWEEAMCPL CKRTRSGALE RP
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