About Uroplakin-3b-like protein 1
Uroplakin-3b-like protein 1 (UPK3BL1) is a protein
from Homo sapiens identified by UniProt accession
B0FP48, 263 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Uroplakin-3b-like protein 1 |
|---|
| UniProt accession | B0FP48 |
|---|
| Gene | UPK3BL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 263 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- diabetes mellitus · score 0.07
- chronotype measurement · score 0.03
- neoplasm · score 0.01
- Insulin resistance · score 0.01
- glioblastoma multiforme · score 0.00
- Eosinophilia · score 0.00
- mesothelioma · score 0.00
- nail-patella syndrome · score 0.00
- glioblastoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B0FP48-F1 | alphafold | PREDICTED | 82.15 | — |
Amino-acid sequence (263 residues)
MDNSWRLGPA IGLSAGQSQL LVSLLLLLTR VQPGTDVAAP EHISYVPQLS NDTLAGRLTL STFTLEQPLG QFSSHNISDL DTIWLVVALS NATQSFTAPR TNQDIPAPAN FSQRGYYLTL RANRVLYQTR GQLHVLRVGN DTHCQPTKIG CNHPLPGPGP YRVKFLVMND EGPVAETKWS SDTRLQQAQA LRAVPGPQSP GTVVIIAILS ILLAVLLTVL LAVLIYTCFN SCRSTSLSGP EEAGSVRRYT THLAFSTPAE GAS
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