About WD repeat-containing protein 64
WD repeat-containing protein 64 (WDR64) is a protein
from Homo sapiens identified by UniProt accession
B1ANS9, 1081 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | WD repeat-containing protein 64 |
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| UniProt accession | B1ANS9 |
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| Gene | WDR64 |
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| Organism | Homo sapiens |
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| Length | 1081 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (10)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.29
- mathematical ability · score 0.29
- bone density · score 0.21
- urate measurement · score 0.21
- drug use measurement · score 0.20
- major depressive disorder · score 0.06
- metabolite measurement · score 0.06
- Crohn's disease · score 0.02
- inflammatory bowel disease · score 0.01
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B1ANS9-F1 | alphafold | PREDICTED | 70.08 | — |
Amino-acid sequence (1081 residues)
MDIRKEKRLN MALQMSNFKK ALNRFEKLVE QTAAQKRDER AGLFIHKEDA IGYDKFYASV QKLFGPDVKN QDVKRFYRKL CNNTDASADW CEIFGYFSSE EDPIASQLDE ENLVFFVSRK RRILISGSRR RDVIKSIVKI PHLDLLITAT QKGLITVFNN QDTSWITGCD YLLQLKRIVA TTERTIIVWD YKAQGSSQEN YFVIKPMDHC LLCVCVVPLP DHLCRDDILL GDDGGFVNRF TVNSDDFGIK QAKSKRKLQN QVLDSKNFKS VKRKLHNDWV MKIRYISALN CFGSCSLDSN HSLVLESLKR LEDNLPVREF SMPRGANTFC YCVKANVIVT GGDDKVIRLW HPNISTKPVG KLVGHMFSIA EIVTNEKDQH VVSLSSAKVF RVWDIQTLSL LQVFHDSQGG PGDMQIYSMI YDANHGMLIT GSSVMDMYPL TRMIQDTKQV PHTHEREINV MLYNKYFHQV LTICSESIIR VWELETGLQV YQILEPHGFN TEVTSAAVDE SGFLFATGAY NGTVRIWDFG SGQEMKVLPE GKDWKEDEHC LRRLIFLKAQ EKHQQLVLAL ERNGTIKMIQ GKEDDIYLMV IWELPDVVPF LQDGKHAVHL RMSTRDRNMA IPFPDVELIV ERNFSQPTDN PTMDLLRVNC IDLLQVEGYN LIAAGTLNGV IILWNFVTST VKKVYRPEDC FTVNPDLHPK HFKINDILFL FRTPECARRS SQDSICSSSQ CESSKGPQSS KGSKQSIHDS EVKGEQTDVM VGKQQPMDKK HPGIANLPEA QPPILVTAHE DGHLRLWTLE GRLLKDMLPF TKHSAISLTS LYTDSCTRIL LAGNVEGHVI LCNISSFLDP PHDEKKFKQL LSWRAHSLEI IQVIYVEEKQ VVLTASIDGS VRLWHALNGH YCGYFGQRRL FELSQTRDFI LPCDVTEYPI EIKEESKFTE KQKYEYPLIF DREKWRKMSS VSLLFKRTPP KAFEVEQDFK FFKSLSSPKI RRYPLEGFVT ENREAGIVFG SLPIYSISSP TSLRFLPLIG VEAQKDSSDG ITGKKKGGHV QREKAPRRRS LKKNLVPQIN LASSFFPAIP K
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