About Killin
Killin (KLLN) is a protein
from Homo sapiens identified by UniProt accession
B2CW77, 178 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Killin |
|---|
| UniProt accession | B2CW77 |
|---|
| Gene | KLLN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (118)
Diseases linked to this target (Open Targets).
- Cowden disease · score 0.41
- neurodegenerative disease · score 0.37
- type 2 diabetes mellitus · score 0.32
- BMI-adjusted waist-hip ratio · score 0.28
- waist-hip ratio · score 0.26
- monocyte count · score 0.25
- systolic blood pressure · score 0.24
- mean platelet volume · score 0.22
- monocyte percentage of leukocytes · score 0.22
- mean corpuscular volume · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B2CW77-F1 | alphafold | PREDICTED | 50.89 | — |
Amino-acid sequence (178 residues)
MDRPGPGSAR PGRTVHVWGY RVEWKVRNGR KLQPSEWAGR GDLGGFKRRW KDTRATVGTT FRRRSRVSLV GELSKFPLPS DSSGGKSSSS FARGALAWCR QRNPNPSCAA AETGARTSLP KERCRGWRLG NWLHKHPHPN TCPRLPACWL PPILTERGER VPKLVPLLAC YPKSKPKD
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