MORF4 family associated protein 1 like 2 (MRFAP1L2)

About MORF4 family associated protein 1 like 2

MORF4 family associated protein 1 like 2 (MRFAP1L2) is a protein from Homo sapiens identified by UniProt accession B2RBV5, 119 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein name	MORF4 family associated protein 1 like 2
UniProt accession	B2RBV5
Gene	MRFAP1L2
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (85)

Diseases linked to this target (Open Targets).

dengue disease · score 0.01
Miyoshi myopathy · score 0.01
diabetes mellitus · score 0.01
cancer · score 0.01
infect · score 0.01
infection · score 0.01
chronic kidney disease · score 0.01
diabetic nephropathy · score 0.01
neoplasm · score 0.01
axial length measurement · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B2RBV5-F1	alphafold	PREDICTED	83.38	—

Amino-acid sequence (119 residues)

MRPVDADEAR EPREEPGSPL SPAPRAGREN LASLERERAR AHWRARRKLL EIQSLLDAIK SEVEAEERGA RAPAPRPRAE AEERVARLCA EAERKAAEAA RMGRRIVELH QRIAGCECC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards