Sperm axonemal maintenance protein CFAP97D1 (CFAP97D1)

About Sperm axonemal maintenance protein CFAP97D1

Sperm axonemal maintenance protein CFAP97D1 (CFAP97D1) is a protein from Homo sapiens identified by UniProt accession B2RV13, 164 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	Sperm axonemal maintenance protein CFAP97D1
UniProt accession	B2RV13
Gene	CFAP97D1
Organism	Homo sapiens
Length	164 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

bone density · score 0.30
ulna fracture · score 0.25
radius fracture · score 0.25
bone fracture · score 0.16
hip bone mineral density · score 0.16
injury · score 0.15
spine bone mineral density · score 0.14
femoral neck bone mineral density · score 0.12
triglyceride measurement · score 0.12
high density lipoprotein cholesterol measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B2RV13-F1	alphafold	PREDICTED	84.71	—

Amino-acid sequence (164 residues)

MNNSLDYLAY PVIVSNHRQS TTFRKKLDFG HYVSHKNRIQ IAKPTVDTKP PVAHTNHILK LSKLQGEQKK INKIEYENKQ LCQKIANAHR GPAKVDCWNE YFSKSLNRET RNRELVRITM ENQGILKRLV DRKPHYDRRA SEIDWQNSRR YIRNTTRYLL SQNE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards