Protein FAM25A (FAM25A)

Homo sapiens — UniProt B3EWG3

Gene: FAM25AHomo sapiensSwissProt reviewed

About Protein FAM25A

Protein FAM25A (FAM25A) is a protein from Homo sapiens identified by UniProt accession B3EWG3, 89 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein nameProtein FAM25A
UniProt accessionB3EWG3
GeneFAM25A
OrganismHomo sapiens
Length89 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (6)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.15
  • Barrett's esophagus · score 0.05
  • esophageal squamous cell carcinoma · score 0.05
  • esophageal adenocarcinoma · score 0.05
  • Colon Sessile Serrated Adenoma/Polyp · score 0.01
  • eosinophilic esophagitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-B3EWG3-F1alphafoldPREDICTED61.06—

Amino-acid sequence (89 residues)

MLGGLGKLAA EGLAHRTEKA TEGAIHAVEE VVKEVVGHAK ETGEKAIAEA IKKAQESGDK KMKEITETVT NTVTNAITHA AESLDKLGQ

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Quick facts

UniProtB3EWG3
GeneFAM25A
OrganismHomo sapiens
Length89
Binders0
Diseases6
View on UniProt