About IQCJ-SCHIP1 readthrough transcript protein
IQCJ-SCHIP1 readthrough transcript protein (IQCJ-SCHIP1) is a protein
from Homo sapiens identified by UniProt accession
B3KU38, 563 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | IQCJ-SCHIP1 readthrough transcript protein |
|---|
| UniProt accession | B3KU38 |
|---|
| Gene | IQCJ-SCHIP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 563 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- neuroimaging measurement · score 0.34
- brain volume measurement · score 0.32
- brain measurement · score 0.25
- metabolite measurement · score 0.25
- smoking initiation · score 0.22
- smoking status measurement · score 0.16
- antisocial behaviour measurement · score 0.13
- substance abuse · score 0.13
- attention deficit hyperactivity disorder · score 0.13
- drug use measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B3KU38-F1 | alphafold | PREDICTED | 57.48 | — |
Amino-acid sequence (563 residues)
MRLEELKRLQ NPLEQVNDGK YSFENHQLAM DAENNIEKYP LNLQPLESKV KIIQRAWREY LQRQEPLGKR SPSPPSVSSE KLSSSVSMNT FSDSSTPDYR EDGMDLGSDA GSSSSSSRAS SQSNSTKVTP CSECKSSSSP GGSLDLVSAL EDYEEPFPVY QKKVIDEWAP EEDGEEEEEE DERDQRGYRD DRSPAREPGD VSARTRSGGG GGRSATTAMP PPVPNGNLHQ HDPQDLRHNG NVVVAGRPSC SRGPRRAIQK PQPAGGRRSG RGPAAGGLCL QPPDGGTCVP EEPPVPPMDW EALEKHLAGL QFREQEVRNQ GQARTNSTSA QKNERESIRQ KLALGSFFDD GPGIYTSCSK SGKPSLSSRL QSGMNLQICF VNDSGSDKDS DADDSKTETS LDTPLSPMSK QSSSYSDRDT TEEESESLDD MDFLTRQKKL QAEAKMALAM AKPMAKMQVE VEKQNRKKSP VADLLPHMPH ISECLMKRSL KPTDLRDMTI GQLQVIVNDL HSQIESLNEE LVQLLLIRDE LHTEQDAMLV DIEDLTRHAE SQQKHMAEKM PAK
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