Zinc finger protein 879 (ZNF879)

About Zinc finger protein 879

Zinc finger protein 879 (ZNF879) is a protein from Homo sapiens identified by UniProt accession B4DU55, 563 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Zinc finger protein 879
UniProt accession	B4DU55
Gene	ZNF879
Organism	Homo sapiens
Length	563 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

body fat distribution · score 0.06
FEV/FVC ratio · score 0.05
cortical thickness · score 0.04
alkaline phosphatase measurement · score 0.04
body height · score 0.03
BMI-adjusted waist circumference · score 0.03
waist-hip ratio · score 0.02
oral squamous cell carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B4DU55-F1	alphafold	PREDICTED	70.60	—

Amino-acid sequence (563 residues)

MARRLLPAHV QESVTFRDVA VFFSQDEWLH LDSAQRALYR EVMLENYSIL VSLGILFSKP KVISQLEQGE DPWMVESGVP QGAHLGWESL FGTIVSKEEN QEVMKKLIID GTFDFKLEKT YINEDKLEKQ QGKKNRLFSK VLVTIKKVYM KERSFKGVEF GKNLGLKSSL IRKPRIVSRG RRPRSQQYSV LFKQLGVNTV RKCYKCNICG KIFLHSSSLS KHQRIHTGEK LYKCKECRKA FSQSSSLTQH LRVHTGEKPY ICSECGKAFS FTTSLIGHQR MHTGERPYKC KECGKTFKGS SSLNNHQRIH TGEKPYKCNE CGRAFSQCSS LIQHHRIHTG EKPYECTQCG KAFTSISRLS RHHRIHTGEK PFHCNECGKV FSYHSALIIH QRIHTGEKPY ACKECGKAFS QSSALIQHQR IHTGEKPYKC NECGKAFSWI SRLNIHHRIH TGEKPYNCKE CGKAFSSHSG VNTHRKIHTG EKPYKCNDCE KAFNQSSALI QHQRIHTGEK PYNCKVCGKA FRQSSSLMTH MRIHTGEKPY KCKECGKAFS QSSSLTNHQR THN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards