Zinc finger protein 736 (ZNF736)

About Zinc finger protein 736

Zinc finger protein 736 (ZNF736) is a protein from Homo sapiens identified by UniProt accession B4DX44, 427 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Zinc finger protein 736
UniProt accession	B4DX44
Gene	ZNF736
Organism	Homo sapiens
Length	427 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

PHF-tau measurement · score 0.31
adolescent idiopathic scoliosis · score 0.31
neurodegenerative disease · score 0.16
eosinophil percentage of leukocytes · score 0.14
Cystic Kidney Disease · score 0.06
Down syndrome · score 0.06
rheumatoid arthritis · score 0.05
X-linked severe congenital neutropenia · score 0.04
Blackfan-Diamond anemia · score 0.04
neutropenia, severe congenital, 2, autosomal dominant · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B4DX44-F1	alphafold	PREDICTED	72.37	—

Amino-acid sequence (427 residues)

MGVLTFRDVA VEFSPEEWEC LDSAQQRLYR DVMLENYGNL VSLGLAIFKP DLMTCLEQRK EPWKVKRQEA VAKHPAGSFH FTAEILPDHD IKDSFQKVIL RKYGSCDLNN LHLKKDYQSV GNCKGQKSSY NGLHQCLSAT HSKTCQCNKC GRGFQLCSIF TEHKDIFSRE KCHKCEECGK DCRLFSDFTR HKKIHTVERC YKCEECGKAF KKFSNLTEHK RVHTGEKPYK CEGCGKTFTC SSTLVKHKRN HTGDRPYKCE ECGKAFKCFS DLTNHKRIHT GEKPYKCEEC NKAYRWFSDL AKHKIIHTGD KPYTCNECGK AFKWFSALSK HKRIHTGEKP YICEECGKAF TRSSTLFNHK RIHMEERPYK CEECSKTFKC FSDLTNHKRI HTGEKPYKCE ECGKASSWFS HLIRHKRIHT REKLHKC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards