SEC14-like protein 6 (SEC14L6)

About SEC14-like protein 6

SEC14-like protein 6 (SEC14L6) is a protein from Homo sapiens identified by UniProt accession B5MCN3, 397 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	SEC14-like protein 6
UniProt accession	B5MCN3
Gene	SEC14L6
Organism	Homo sapiens
Length	397 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

white matter microstructure measurement · score 0.13
neuroimaging measurement · score 0.11
apolipoprotein A 1 measurement · score 0.10
brain measurement · score 0.09
brain volume measurement · score 0.09
glycerophospholipid measurement · score 0.06
high density lipoprotein cholesterol measurement · score 0.06
sporadic Creutzfeld Jacob disease · score 0.05
body height · score 0.04
HbA1c measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B5MCN3-F1	alphafold	PREDICTED	94.19	—

Amino-acid sequence (397 residues)

MSGQVGDLSP SQEKSLAQFR ENIQDVLSAL PNPDDYFLLR WLQARSFDLQ KSEDMLRKHM EFRKQQDLAN ILAWQPPEVV RLYNANGICG HDGEGSPVWY HIVGSLDPKG LLLSASKQEL LRDSFRSCEL LLRECELQSQ KLGKRVEKII AIFGLEGLGL RDLWKPGIEL LQEFFSALEA NYPEILKSLI VVRAPKLFAV AFNLVKSYMS EETRRKVVIL GDNWKQELTK FISPDQLPVE FGGTMTDPDG NPKCLTKINY GGEVPKSYYL CKQVRLQYEH TRSVGRGSSL QVENEILFPG CVLRWQFASD GGDIGFGVFL KTKMGERQRA REMTEVLPSQ RYNAHMVPED GILTCLQAGS YVLRFYNTYS LVHSKRISYT VEVLLPDQTF MEKMEKF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards