About Rab GTPase-activating protein 1-like, isoform 10
Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L) is a protein
from Homo sapiens identified by UniProt accession
B7ZAP0, 253 residues long.
MolForge cross-references it against 0 known binders and
94 disease associations.
Target properties
| Protein name | Rab GTPase-activating protein 1-like, isoform 10 |
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| UniProt accession | B7ZAP0 |
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| Gene | RABGAP1L |
|---|
| Organism | Homo sapiens |
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| Length | 253 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (94)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- osteoarthritis · score 0.30
- body mass index · score 0.29
- neuroticism measurement · score 0.28
- self reported educational attainment · score 0.28
- neutrophil count · score 0.27
- myeloid white cell count · score 0.27
- cholesteatoma · score 0.26
- smoking status measurement · score 0.26
- lean body mass · score 0.26
Amino-acid sequence (253 residues)
MIENSSWSMT FEERENRRLQ EASMRLEQEN DDLAHELVTS KIALRNDLDQ AEDKADVLNK ELLLTKQRLV ETEEEKRKQE EETAQLKEVF RKQLEKAEYE IKKTTAIIAE YKQICSQLST RLEKQQAASK EELEVVKGKM MACKHCSDIF SKEGALKLAA TGREDQGIET DDEKDSLKKQ LREMELELAQ TKLQLVEAKC KIQELEHQRG ALMNEIQAAK NSWFSKTLNS IKTATGTQPL QPAPVTQPPK EST
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