About Uncharacterized protein C21orf140
Uncharacterized protein C21orf140 (C21orf140) is a protein
from Homo sapiens identified by UniProt accession
B9A014, 251 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Uncharacterized protein C21orf140 |
|---|
| UniProt accession | B9A014 |
|---|
| Gene | C21orf140 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 251 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.18
- myocardial infarction · score 0.17
- FEV/FVC ratio · score 0.16
- pulmonary function measurement · score 0.13
- PHF-tau measurement · score 0.12
- angina pectoris · score 0.12
- pulse pressure measurement · score 0.12
- BMI-adjusted waist-hip ratio · score 0.12
- waist-hip ratio · score 0.12
- migraine disorder · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B9A014-F1 | alphafold | PREDICTED | 81.02 | — |
Amino-acid sequence (251 residues)
MPRFASPLLR NVIIRSQFDG IKRKQCLQYL KTLRTLQYDG FKTVYFGETN IPESLVTGED ISDGYFIQTP TWCIVHAAGS QGWVPWKYRV FLRDELCIKQ EDSLFSEFCD VVRKAYGKCV IVVKERRQQE EQRPKEDREA EGQFYIPTVI SLASIMCCPE VAKSCGHELL SLPSPCNYLN PLDSAWSSLK WFIINNRNEF CLQSIDSGYS YQCILFSNLI SKGIERINAS KWRTLTSKVR RWENYYLGKF S
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